Department of Neurology
Patient Care
Department Facts
Dr. Clay JohnstonS. Claiborne Johnston, MD, PhD

Professor of Neurology and Epidemiology
Associate Vice Chancellor of Research
Director, UCSF Clinical and Translational Science Institute


Phone: 415-502-7487
Fax: 415-476-3428
Box #: 0114

Dr. S. Claiborne Johnston is Associate Vice Chancellor of Research, director of the Clinical and Translational Science Institute, Professor of Neurology and Epidemiology, and director of the Stroke Service at the University of California, San Francisco. He received his undergraduate education at Amherst College and completed medical school at Harvard University. He received a Ph.D. in epidemiology from the University of California, Berkeley. He completed his residency in Neurology at UCSF, where he later trained in Vascular Neurology.

Dr. Johnston has authored more than 200 publications in scientific journals and has won several national awards for his research and teaching. He has led several large cohort studies of cerebrovascular disease and three multicenter randomized trials. Dr. Johnston studies stroke treatment and prevention using the tools of computer science and epidemiology.

Dr. Johnston is the Executive Vice Editor of the Annals of Neurology and has served on the editorial boards of several other journals. He has been honored with the American Academy of Neurology's Pessin Prize for Stroke Leadership and the American Stroke Association's Siekert New Investigator Award. He was a member of the California Health Disease and Stroke Prevention Advisory Council, which advises the Department of Health Services, and was co-director of Prevention Education Programs for the National Stroke Association.

Dr. Johnston's research interests include:

* Transient ischemic attack evaluation, prognosis, and treatment
* Cerebral aneurysm and subarachnoid hemorrhage treatment
* Cognitive dysfunction and stroke risk factors
* Infection and stroke risk
* Optimization of the prevention of stroke
* The health economics of clinical research

Selected publications:

SC Johnston, CB Wilson, VV Halbach, RH Higashida, CF Dowd, MW McDermott, CB Applebury, TL Farley, DR Gress, "Endovascular and surgical treatment of unruptured cerebral aneurysms: comparison of risks," Ann Neurol, 48:11-19, 2000.

SC Johnston, DR Gress, WS Browner, S Sidney, "Short-term prognosis after emergency-department diagnosis of transient ischemic attack," JAMA, 284:2901-6, 2000.

SC Johnston, T Hennemen, CE McCulloch, M van der Laan, "Modeling treatment effects on binary outcomes with grouped-treatment variables and individual covariates," Amer J Epidemiol 156: 753-760, 2002.

SC Johnston, JD Rootenberg, S Katrak, WS Smith, JS Elkins, "Effect of a US National Institutes of Health programme of clinical trials on public health and costs," Lancet, 367:1319-27, 2006.

SC Johnston, PM Rothwell, MN Huynh-Huynh, MF Giles, JS Elkins, S Sidney, "Validation and refinement of scores to predict very early stroke risk after transient ischemic attack," Lancet, 369:283-292, 2007.

SC Johnston, S Mendis, CD Mathers, "Global variation in stroke burden and mortality: estimates from monitoring, surveillance, and modelling," Lancet Neurol, 8:345-54, 2009.

Link to my publications on PubMed


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