There are several ongoing projects in the lab studying the developmental regulation of axonal connectivity in the cortex. Areas of particular focus are the development of cortical connectivity by axon guidance molecules expressed in the developing hippocampus and cortical hem.
Development of Cortical Connectivity
Thalamocortical axons marked by a transgenic marker line as they travel in the subcortical white matter and terminate in the barrel fields in Layer 4 of the somatosensory cortex
Lipophilic dye labeling of thalamocortical afferents in a mutant with defective projections from the thalamus to cortex.