Stroke Sciences Group
About Us
Education & Training
Patient Care
Department of Neurology

Research Services



Buffy Hespelt, Buffy.Hespelt@ucsfmedctr.org
phone 415-353-8897
fax 415-353-8705


Founded in 2002, the Stroke Sciences Group (SSG) is an active division of the Department of Neurology at the University of California, San Francisco. The group's overall goal is to study the epidemiology and natural history of neurovascular disease, and then apply this knowledge to the development of management strategies. As an academic research organization with over 10 years of experience coordinating domestic and international multicenter drug and device clinical trials and observational studies, we work closely with the UCSF Clinical and Translational Science Institute (CTSI) and the San Francisco Coordinating Center (SFCC). SSG has been responsible for launching and coordinating many complex multicenter studies funded by the NIH, industry, and the CDC. Examples of supported projects include:


We are a team of 20 physicians, scientists, nurses, clinical research coordinators and biostatisticians. In addition to our Core group, we have a large network of partnered specialists who are available when additional expertise is needed for a project. Our internationally recognized leaders include S. Claiborne Johnston, Wade Smith, J. Donald Easton, and Heather Fullerton, who have led many multicenter studies.

We specialize in the disease areas of adult ischemic stroke and TIA, pediatric stroke, cerebral aneurysms and vascular malformations.  The SSG has a proven track record in protocol development, site selection, subject recruitment and retention, site coordination/ monitoring, data collection, data management, data analysis, neuroimaging systems and process management, adjudication, committee oversight, and publications.

We provide services in the following areas:

Trial planning

Trial execution



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