Ji-Eun Kim , Ph.D.

Position: Post-doctoral Fellow
Degree(s): Ph.D.(2010)
Born: Seoul, South Korea
In Lab Since: 2010

Research Interests

Selected Publications

  • Jo SM, Ryu HJ, Kim JE, Yeo SI, Kim MJ, Choi HC, Song HK, Kang TC. Up-regulation of endothelial endothelin-1 expression prior to vasogenic edema formation in the rat piriform cortex following status epilepticus. Neurosci Lett. 2011 Jun 29.
  • Kim JE, Yeo SI, Ryu HJ, Chung CK, Kim MJ, Kang TC. Changes in TWIK-related Acid Sensitive K(+)-1 and -3 Channel Expressions from Neurons to Glia in the Hippocampus of Temporal Lobe Epilepsy Patients and Experimental Animal Model. Neurochem Res. 2011 Jun 28.
  • Kim JE, Ryu HJ, Kang TC. P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor- a-mediated pathway in the rat hippocampus following status epilepticus. J Neuroinflammation. 2011 Jun 2;8:62.
  • Ryu HJ, Kim JE, Yeo SI, Kim DW, Kwon OS, Choi SY, Kang TC. F-actin depolymerization accelerates clasmatodendrosis via activation of lysosome-derived autophagic astroglial death. Brain Res Bull. 2011 Jul 15;85(6):368-73.
  • Ryu HJ, Kim JE, Yeo SI, Kang TC. p65/RelA-Ser529 NF-?B Subunit Phosphorylation Induces Autophagic Astroglial Death (Clasmatodendrosis) Following Status Epilepticus. Cell Mol Neurobiol. 2011 May 20.
  • Ryu HJ, Kim JE, Yeo SI, Kim MJ, Jo SM, Kang TC. RelA/p65-serine 536 nuclear factor-kappa B phosphorylation is related to vulnerability to status epilepticus in the rat hippocampus. Neuroscience. 2011 Jul 28;187:93-102.
  • Yeo SI, Ryu HJ, Kim JE, Chun W, Seo CH, Lee BC, Choi IG, Sheen SH, Kang TC. The effects of electrical shock on the expressions of aquaporin subunits in the rat spinal cords. Anat Cell Biol. 2011 Mar;44(1):50-9.
  • Kim JE, Kang TC. The P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptor-mediated seizure susceptibility in mice. J Clin Invest. 2011 May 2;121(5):2037-47.
  • Yeo SI, Kim JE, Ryu HJ, Seo CH, Lee BC, Choi IG, Kim DS, Kang TC. The roles of fractalkine/CX3CR1 system in neuronal death following pilocarpine-induced status epilepticus. J Neuroimmunol. 2011 May;234(1-2):93-102.
  • Sheen SH, Kim JE, Ryu HJ, Yang Y, Choi KC, Kang TC. Decrease in dystrophin expression prior to disruption of brain-blood barrier within the rat piriform cortex following status epilepticus. Brain Res. 2011 Jan 19;1369:173-83.
  • Kim DW, Yeo SI, Ryu HJ, Kim JE, Song HK, Kwon OS, Choi SY, Kang TC. Effects of creatine and ß- guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models. BMC Neurosci. 2010 Oct 28;11:141.
  • Kim JE, Ryu HJ, Yeo SI, Kang TC. P2X7 receptor regulates leukocyte infiltrations in rat frontoparietal cortex following status epilepticus. J Neuroinflammation. 2010 Oct 12;7:65.
  • Kim JE, Yeo SI, Ryu HJ, Kim MJ, Kim DS, Jo SM, Kang TC. Astroglial loss and edema formation in the rat piriform cortex and hippocampus following pilocarpine-induced status epilepticus. J Comp Neurol. 2010 Nov 15;518(22):4612-28.
  • Kim JE, Ryu HJ, Yeo SI, Kang TC. P2X7 receptor differentially modulates astroglial apoptosis and clasmatodendrosis in the rat brain following status epilepticus. Hippocampus. 2010 Sep 16.
  • Kim JE, Ryu HJ, Kim MJ, Kim DW, Kwon OS, Choi SY, Kang TC. Pyridoxal-5'-phosphate phosphatase/chronophin induces astroglial apoptosis via actin-depolymerizing factor/cofilin system in the rat brain following status epilepticus. Glia. 2010 Dec;58(16):1937-48.
  • Choi HC, Kim YI, Song HK, Kim JE, Kim DS, Kang TC. Effects of selective serotonin reuptake inhibitors on GABAergic inhibition in the hippocampus of normal and pilocarpine induced epileptic rats. Brain Res. 2010 Oct 21;1357:131-41.
  • Ryu HJ, Kim JE, Kim MJ, Kwon HJ, Suh SW, Song HK, Kang TC. The protective effects of interleukin-18 and interferon-? on neuronal damages in the rat hippocampus following status epilepticus. Neuroscience. 2010 Oct 27;170(3):711-21.
  • Ryu HJ, Kim JE, Yeo SI, Kim DS, Kwon OS, Choi SY, Kang TC. Potential roles of D-serine and serine racemase in experimental temporal lobe epilepsy. J Neurosci Res. 2010 Aug 15;88(11):2469-82.
  • Kim JE, Choi HC, Song HK, Jo SM, Kim DS, Choi SY, Kim YI, Kang TC. Levetiracetam inhibits interleukin-1 beta inflammatory responses in the hippocampus and piriform cortex of epileptic rats. Neurosci Lett. 2010 Mar 3;471(2):94-9.
  • Lee SM, Kim JE, Sohn JH, Choi HC, Lee JS, Kim SH, Kim MJ, Choi IG, Kang TC. Down-regulation of delayed rectifier K+ channels in the hippocampus of seizure sensitive gerbils. Brain Res Bull. 2009 Dec 16;80(6):433-42.
  • Choi KC, Kwak SE, Kim JE, Sheen SH, Kang TC. Enhanced glial fibrillary acidic protein-delta expression in human astrocytic tumor. Neurosci Lett. 2009 Oct 9;463(3):182-7.
  • Kim JE, Ryu HJ, Yeo SI, Seo CH, Lee BC, Choi IG, Kim DS, Kang TC. Differential expressions of aquaporin subtypes in astroglia in the hippocampus of chronic epileptic rats. Neuroscience. 2009 Oct 20;163(3):781-9.
  • Kwak SE, Kim JE, Kim DW, Kwon OS, Choi SY, Kang TC. Enhanced pyridoxal 5'-phosphate synthetic enzyme immunoreactivities do not contribute to GABAergic inhibition in the rat hippocampus following pilocarpine- induced status epilepticus. Neuroscience. 2009 Mar 31;159(3):1108-18.
  • Kim JE, Kim DW, Kwak SE, Ryu HJ, Yeo SI, Kwon OS, Choi SY, Kang TC. Pyridoxal-5'-phosphate phosphatase/ chronophin inhibits long-term potentiation induction in the rat dentate gyrus. Hippocampus. 2009 Nov;19(11):1078-89.
  • Kim JE, Kwak SE, Kang TC. Upregulated TWIK-related acid-sensitive K+ channel-2 in neurons and perivascular astrocytes in the hippocampus of experimental temporal lobe epilepsy. Epilepsia. 2009 Apr;50(4):654-63.
  • Kim JE, Kwak SE, Jo SM, Kang TC. Blockade of P2X receptor prevents astroglial death in the dentate gyrus following pilocarpine-induced status epilepticus. Neurol Res. 2009 Nov;31(9):982-8.
  • Kwak SE, Kim JE, Choi HC, Song HK, Kim YI, Jo SM, Kang TC. The expression of somatostatin receptors in the hippocampus of pilocarpine-induced rat epilepsy model. Neuropeptides. 2008 Oct-Dec;42(5-6):569-83.
  • Kim DS, Kim JE, Kwak SE, Choi KC, Kim DW, Kwon OS, Choi SY, Kang TC. Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. J Comp Neurol. 2008 Dec 10;511(5):581-98.
  • Kwak SE, Kim JE, Kim DW, Kwon OS, Choi SY, Kang TC. Pyridoxine 5'-phosphate oxidase, not pyridoxal kinase, involves in long-term potentiation induction in the rat dentate gyrus. Hippocampus. 2009 Jan;19(1):45-56.
  • Kim JE, Kwak SE, Choi SY, Kang TC. Region-specific alterations in astroglial TWIK-related acid-sensitive K+-1 channel immunoreactivity in the rat hippocampal complex following pilocarpine-induced status epilepticus. J Comp Neurol. 2008 Oct 10;510(5):463-74.
  • Kwak SE, Kim JE, Kim SC, Kwon OS, Choi SY, Kang TC. Hyperthermic seizure induces persistent alteration in excitability of the dentate gyrus in immature rats. Brain Res. 2008 Jun 24;1216:1-15.
  • Kim JE, Kwak SE, Choi HC, Song HK, Kim YI, Jo SM, Kang TC. Voltage-gated Na+ channel II immunoreactivity is selectively up-regulated in hippocampal interneurons of seizure sensitive gerbils. Neurosci Lett. 2008 Jun 27;438(3):295-9.
  • Kang TC, Kang JH, Kim HT, Lee SJ, Choi UK, Kim JE, Kwak SE, Kim DW, Choi SY, Kwon OS. Anticonvulsant characteristics of pyridoxyl-gamma-aminobutyrate, PL-GABA. Neuropharmacology. 2008 May;54(6):954-64.
  • Kim JE, Kim DW, Kwak SE, Kwon OS, Choi SY, Kang TC. Potential role of pyridoxal-5'-phosphate phosphatase/ chronopin in epilepsy. Exp Neurol. 2008 May;211(1):128-40.
  • Kim DS, Kim JE, Kwak SE, Choi HC, Song HK, Kimg YI, Choi SY, Kang TC. Up-regulated astroglial TWIK-related acid-sensitive K+ channel-1 (TASK-1) in the hippocampus of seizure-sensitive gerbils: a target of anti-epileptic drugs. Brain Res. 2007 Dec 14;1185:346-58.
  • Kim JE, Kim DS, Kwak SE, Choi HC, Song HK, Choi SY, Kwon OS, Kim YI, Kang TC. Anti-glutamatergic effect of riluzole: comparison with valproic acid. Neuroscience. 2007 Jun 15;147(1):136-45.
  • Kim DS, Kim JE, Kwak SE, Kim DW, Choi SY, Kwon OS, Kang TC. Seizure activity selectively reduces 5-HT1A receptor immunoreactivity in CA1 interneurons in the hippocampus of seizure-prone gerbils. Brain Res. 2007 Jun 18;1154:181-93.
  • Kim DS, Kim JE, Kwak SE, Won MH, Kang TC. Seizure activity affects neuroglial Kv1 channel immunoreactivities in the gerbil hippocampus. Brain Res. 2007 Jun 2;1151:172-87.
  • Kim JE, Kwak SE, Kim DS, Won MH, Choi HC, Song HK, Kim YI, Kang TC. Up-regulation of P/Q-type voltage-gated Ca2+ channel immunoreactivity within parvalbumin positive neurons in the rat hippocampus following status epilepticus. Neurosci Res. 2007 Mar;57(3):379-86.
  • Kim DS, Kwak SE, Kim JE, Won MH, Kang TC. The co-treatments of vigabatrin and P2X receptor antagonists protect ischemic neuronal cell death in the gerbil hippocampus. Brain Res. 2006 Nov 20;1120(1):151-60.
  • Kwak SE, Kim JE, Kim DS, Won MH, Lee HJ, Choi SY, Kwon OS, Kim JS, Kang TC. Differential paired-pulse responses between the CA1 region and the dentate gyrus are related to altered CLC-2 immunoreactivity in the pilocarpine-induced rat epilepsy model. Brain Res. 2006 Oct 18;1115(1):162-8.
  • Kim DS, Kwak SE, Kim JE, Kim JS, Won MH, Kang TC. The selective effects of somatostatin- and GABA-mediated transmissions on voltage gated Ca2+ channel immunoreactivity in the gerbil hippocampus. Brain Res. 2006 Oct 18;1115(1):200-8.
  • Kang TC, Kim DS, Kwak SE, Kim JE, Won MH, Kim DW, Choi SY, Kwon OS. Epileptogenic roles of astroglial death and regeneration in the dentate gyrus of experimental temporal lobe epilepsy. Glia. 2006 Sep;54(4):258-71.
  • Kim DS, Kwak SE, Kim JE, Jung JY, Won MH, Choi SY, Kwon OS, Kang TC. Transient ischaemia affects plasma membrane glutamate transporter, not vesicular glutamate transporter, expressions in the gerbil hippocampus. Anat Histol Embryol. 2006 Aug;35(4):265-70.
  • Kang TC, Kim DS, Kim JE, Kwak SE, Yoo KY, Hwang IK, Jung JY, Won MH, Kwon OS, Choi SY. Altered expression of K+ -Cl- cotransporters affects fast paired-pulse inhibition during GABA receptor activation in the gerbil hippocampus. Brain Res. 2006 Feb 9;1072(1):8-14.
  • Kim DS, Kwak SE, Kim JE, Won MH, Suh JG, Oh YS, Kang TC. The effect of P2X receptor activity on GABAA receptor-mediated inhibition in the gerbil hippocampus. Brain Res. 2005 Dec 14;1065(1-2):125-31.
  • Kim JE, Kwak SE, Kim DS, Won MH, Kwon OS, Choi SY, Kang TC. Reduced calcium binding protein immunoreactivity induced by electroconvulsive shock indicates neuronal hyperactivity, not neuronal death or deactivation. Neuroscience. 2006;137(1):317-26.
  • Kim DS, Kwak SE, Kim JE, Won MH, Choi HC, Song HK, Kim YI, Choi SY, Kang TC. The effect of topiramate on GABA(B) receptor, vesicular GABA transporter and paired-pulse inhibition in the gerbil hippocampus. Neurosci Res. 2005 Dec;53(4):413-20.
  • Kwak SE, Kim JE, Kim DS, Won MH, Choi HC, Kim YI, Song HK, Choi SY, Kang TC. Differential effects of vigabatrin and zonisamide on the neuropeptide Y system in the hippocampus of seizure prone gerbil. Neuropeptides. 2005 Oct;39(5):507-13.
  • Kang TC, Kim DS, Kwak SE, Kim JE, Kim DW, Kang JH, Won MH, Kwon OS, Choi SY. Valproic acid reduces enhanced vesicular glutamate transporter immunoreactivities in the dentate gyrus of the seizure prone gerbil. Neuropharmacology. 2005 Nov;49(6):912-21.
  • Kim DS, Kwak SE, Kim JE, Won MH, Choi HC, Song HK, Kwon OS, Kim YI, Choi SY, Kang TC. Bilateral enhancement of excitation via up-regulation of vesicular glutamate transporter subtype 1, not subtype 2, immunoreactivity in the unilateral hypoxic epilepsy model. Brain Res. 2005 Sep 7;1055(1-2):122-30.
  • Kwak SE, Kim JE, Kim DS, Jung JY, Won MH, Kwon OS, Choi SY, Kang TC. Effects of GABAergic transmissions on the immunoreactivities of calcium binding proteins in the gerbil hippocampus. J Comp Neurol. 2005 May 2;485(2):153-64.
  • Kang TC, Kim DS, Yoo KY, Hwang IK, Kwak SE, Kim JE, Jung JY, Won MH, Suh JG, Oh YS. Elevated voltage-gated Ca2+ channel immunoreactivities in the hippocampus of seizure-prone gerbil. Brain Res. 2004 Dec 17;1029(2):168- 78.
    • Last modified: August 20 2011